Advances in analytical chemistry?
نویسنده
چکیده
where Ca and Cb are the analytical (starting) concentration of the acid and base, respectively. Over the past 50 years, chemists have elaborated upon Charlot’s method so that variations upon the “proton accounting” theme are plentiful. The investigators are correct to note that a properly written proton balance equation will not violate the conservation of charge and makes explicit use of charge balance unnecessary, reaffirming Butler’s observation made some 40 year earlier (1). However, the investigators fail to cite de Levie’s proton condition (4), Morel’s tableau method (7), Guenther’s n-bar equation (5), or Butler’s strong ion difference (SID; expressed as a function of the analytic concentration of reagents) (2). Although inapplicable to systems far from equilibrium, these models yield good results after equilibrium has been achieved. As an example, de Levie (4) derived the following formula to predict the equilibrium pH of a titration (e.g., the addition of strong acid or base to a sample containing a buffer solution), and to graph the resulting titration curves [H ] Vs i CsiFsi
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ورودعنوان ژورنال:
- American journal of physiology. Renal physiology
دوره 298 2 شماره
صفحات -
تاریخ انتشار 2010